When you see another being wronged it can be hard to stop yourself from taking action against whomever caused the wrong. Taking up the reproach of another is when your best friend is bullied at school and you take it upon yourself to do harm to the bullies for doing harm to your friend. You have “taken up the reproach” your best friend endured and made it your own. You take ownership of the shame and humiliation or even physical damages your friend suffered as your own and decide to get revenge. You make a conscious decision to do the one perceived as the bully harm. You commit iniquity. Creator GOD does not allow iniquity. Find a different way or outlet to bring justice for your friend. Do not stick your nose in other peoples business. Take heed to yourself.